Actor Nakuti Gatwa will play the doctor in the Doctor Who show, the BBC announced on Sunday.
In a historic casting selection that marks the first time a black man has been chosen to star in the show's central role full-time.
Known for his work on the Netflix series Sex Education, Gatwa, 29, is one of the youngest doctors ever.
"There are no words to describe how I feel. There is a mix of highly regarded, overly excited and definitely a little scared," Gatwa said in a press release.
"Unlike Doctor, I can only have one heart but I am giving it all to this show."
Gatwa was born in Rwanda and raised in Scotland.
He began his professional acting career eight years ago after graduating from the Royal Conservatoire of Scotland, one of the top performing arts schools in the world.
In Netflix's heated series Sex Education, Gatwa plays the vivacious Eric Ephiong, a gay high school student.
As a gay black teen who is the show's main character's best friend,
Eric's role as a "gay sidekick" or "black best friend" for a straight white male protagonist could have been a trap of clichés.
The new season of Doctor Who also marked the return of showrunner Russell T. Davis, who helped revive the show in 2005 after a 15-year hiatus.